Sulconazle Nitrate
- Product Name
- Sulconazle Nitrate
- CAS No.
- 82382-23-8
- Chemical Name
- Sulconazle Nitrate
- Synonyms
- Sulcozle Nitrate;Sulconazle Nitrate;SULCONAZOLE NITRATE;(±)-Sulconazole nitrat;Sulconazle Nitrate USP/EP/BP;SULCONAZOLE NITRATE FPC(CRM STANDARD) USP/EP/BP;1-[2-(4-Chlorobenzylthio)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate
- CBNumber
- CB02131212
- Molecular Formula
- C18H15Cl3N2S.HNO3
- Formula Weight
- 460.76
- MOL File
- 82382-23-8.mol
Sulconazle Nitrate Property
- Melting point:
- 148-153°C
- storage temp.
- Refrigerator
- solubility
- Acetonitrile (Slightly, Heated), Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Off-White
- CAS DataBase Reference
- 82382-23-8
N-Bromosuccinimide Price
- Product number
- J98556
- Product name
- Sulconazole nitrate
- Packaging
- 1g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- API0007242
- Product name
- Sulconazole nitrate
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $224.7
- Updated
- 2021/12/16
- Product number
- K466
- Product name
- Sulconazole nitrate
- Packaging
- 5g
- Price
- $394
- Updated
- 2021/12/16
- Product number
- API0007242
- Product name
- Sulconazole nitrate
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $638.39
- Updated
- 2021/12/16
- Product number
- K466
- Product name
- Sulconazole nitrate
- Packaging
- 10g
- Price
- $641
- Updated
- 2021/12/16
Sulconazle Nitrate Chemical Properties,Usage,Production
Description
Sulconazole nitrate is an imidazole antifungal agent closely related to econazole. It is effective in the topical treatment of a broad spectrum of superficial fungal infections.
Originator
Syntex (USA)
Uses
Antifungal.
Definition
ChEBI: Sulconazole nitrate is an organic nitrate salt, a conazole antifungal drug and an imidazole antifungal drug.
brand name
Exelderm (Westwood-Squibb).
Biological Activity
Sulconazole Nitrate is an imidazole derivative with broad-spectrum antifungal activity.
Clinical Use
1-[2,4-Dichloro-β-[p-chlorobenzyl)thio]phenethyl]imidazolemononitrate (Exelderm) is the white crystalline nitricacid salt of sulconazole. It is sparingly soluble in water butsoluble in ethanol. The salt is used in a solution and a cream in 1% concentration for the treatment of local tinea infections,such as jock itch, athlete’s foot, and ringworm.
in vitro
Sulconazole Nitrate possesses a broad spectrum of activity in vitro against dermatophytes, yeasts and some Gram-positive bacteria at concentrations below 5 mg/L in vitro. It has been shown that against representatives of pathogenic yeasts, dermatophytes and Aspergilli, the RIF values of sulconazole are broadly similar to those of other imidazoles. The fungicidal potency of sulconazole in vitro depends on its concentration and on the growth phase of the inoculum cells. Sulconazole has also demonstrated antibacterial activity in vitro, with MIC values below 12.5 mg/L.
in vivo
The efficacy and safety of sulconazole 1% cream has been demonstrated in controlled clinical studies in patients with superficial dermatophyte or yeast infections. To minimise the risk of reinfection treatment should continue for 3 weeks in Candida infections, tinea cruris, tinea corporis and pityriasis versicolor, and for 4 weeks in patients with tinea pedis.
Sulconazle Nitrate Preparation Products And Raw materials
Raw materials
Preparation Products
Sulconazle Nitrate Suppliers
- Tel
- 021-58955995
- Fax
- 609-228-5909
- sales@medchemexpress.cn
- Country
- United States
- ProdList
- 4863
- Advantage
- 58
- Tel
- +1-800-259-7612
- Fax
- +1-800-259-7612
- info@musechem.com
- Country
- United States
- ProdList
- 4662
- Advantage
- 60
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
- ProdList
- 6393
- Advantage
- 58
View Lastest Price from Sulconazle Nitrate manufacturers
- Product
- Sulconazole nitrate 82382-23-8
- Price
- US $0.01-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50 tons
- Release date
- 2020-05-12
- Product
- Sulconazle Nitrate 82382-23-8
- Price
- US $60.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2023-03-28
- Product
- Sulconazle Nitrate 82382-23-8
- Price
- US $60.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2023-03-28